Drug permeation study through biological membrane barriers

A Novel Composite Membrane for pH Responsive Permeation

Objective(s) In this study, a kind of pH sensitive composite membrane was prepared and drug permeation through it was investigated in terms of pH. Rationale of this study originated from the fact that a pH change which may be a result of a disease state in the body can trigger drug release. Materials and Methods  Here, a kind of pH sensitive composite membrane containing different nanoparticle ...

Preparation and Investigation of Poly (N-isopropylacrylamide-acrylamide) Membranes in Temperature Responsive Drug Delivery

Objective(s) Physiological changes in the body may be utilized as potential triggers for controlled drug delivery. Based on these mechanisms, stimulus-responsive drug delivery has been developed. Materials and Methods In this study, a kind of poly (N-isopropylacrylamide-acrylamide) membrane was prepared by radical copolymerization. Changes in swelling ratios and diameters of the membrane wer...

Novel Electroless Plating of Ruthenium for Fabrication of Palladium-Ruthenium Composite Membrane on PSS Substrate and Its Characterization

This paper focused on a novel method of electroless plating ruthenium (Ru) on solid or porous substrates like porous stainless steel (PSS) discs or ceramic tubes. A novel complexing plating bath of Ru was developed. It is proven that Ru can be deposited directly on these substrates by the bath at a temperature of 328 K and strong alkaline environment. TGA, SEM, EDX and XRD confirmed the success...

Using PERVAP 2201 Membrane in Vapor Permeation Facilitated Isopropyl Propionate Production through Esterification Reaction

An In-Vitro Iontophoretic Permeation Study of Nicotine through Rat Skin

Nicotine transdermal systems are being used as an aid to smoking cessation programs. As the kinetics of nicotine delivery is important in success of a smoking cessation program, rapid and high input of nicotine is required, which is not possible by passive methods and requires enhancement strategies such as iontophoresis. Iontophoretic permeation, of nicotine looks promising, based on published...